The State Health Systems Resource Centre, Kerala (SHSRC-K), was established in 2008-09 as a dedicated technical support organization under the Department of Health & Family Welfare, Government of Kerala. Modelled after the National Health Systems Resource Centre (NHSRC), New Delhi, SHSRC-K plays a pivotal role in strengthening the state’s health systems by providing expert guidance on the formulation and implementation of effective health policies and strategies. Recognizing its growing impact and potential, the Government of Kerala granted SHSRC-K autonomous status in 2013-14. This enabled the organization to expand its mandate with a stronger focus on evidence generation which in turn facilitates the delivery of regular policy and strategic advice while mobilizing technical assistance to address critical health system challenges. Today, SHSRC-K serves as a trusted advisor to the government, fostering innovation and evidence-based approaches to improve public health outcomes across Kerala.